研究成果

科研項目

本科、博士畢業于402永利,2017年3月獲得博士學位,2014-2016年在哈佛大學聯合培養2年,2017-2021年在康奈爾大學從事博士後研究,2021年4月入職402永利,擔任教授、博士生導師,入選上海市領軍人才(海外)、高等教育人才攬蓄行動A類(學科領軍)、402永利高層次海外引進人才。長期專注于纖維基生物醫用材料的應用基礎研究,包括人工胰腺治療糖尿病等應用,主持國自然面上、國自然外國資深學者研究基金項目、國自然中白國際合作交流項目、國自然中韓國際合作交流項目、上海市細胞與基因治療專項項目、學科創新領域培育等項目,總計經費600餘萬元,發表SCI論文34篇,被Nature, Science, Cell等高水平雜志引用3600餘次,H因子21。其中,以第一作者或通訊作者發表SCI論文19篇,包括Advanced Materials, Advanced Functional Materials, Nano Letters, Nano Energy 等高影響力期刊,部分成果被Advanced Materials等期刊作為封面論文發表,4 篇一作SCI論文被引>200 次,3篇被引>400次,申請發明專利5項,起草行業标準2項。擔任《Polymers》編委及客座主編,《Biofunctional Materials》副主編,《402永利學報(自然科學版)》和《402永利學報(英文版)》編委,《現代紡織技術》青年編委,捷克基金會評審專家,中國家用紡織品行業協會智庫專家,曾擔任全國功能材料與器件大會生物醫用材料專題主席,受邀學術報告10餘次,榮獲中國紡織工業聯合會科技進步獎二等獎、上海市優秀畢業生、王善元優秀博士論文等榮譽。

•國家自然科學基金面上項目,基于長期高效分子輸運機制的三維人工胰腺構築與應用,2023.1-2026.12,54萬元,在研,主持。

•國家自然科學基金外國資深學者研究基金項目,光交聯生物高分子和光聚合三維打印,2025.1-2026.12,160萬元,主持

國家自然科學基金中白國際合作與交流項目,改性聚氨酯納米纖維三維人工胰腺的研制及其長期抗纖維囊化機制,2024.1-2025.12,20萬元,主持。

國家自然科學基金中韓國際合作與交流項目,水合作用調控納米纖維增強果膠水凝膠人工胰腺的長期抗纖維囊化機制,2024.7-2026.6,15萬元,主持。

上海市細胞與基因治療專項項目,人類胰島體外擴增技術的開發和疊代,2023.12-2026.11,150萬元,在研,共主持。

上海市領軍人才(海外),纖維基生物材料,2022.1-2024.12,75萬,在研,主持。

402永利高層次引進人才,高性能生物醫用材料,2021.4-2024.3,150萬元,在研,主持。

學科創新領域培育項目,纖維基三維人工胰腺的精準構築及長期高效分子輸運機制,2023.6-2026.5,50萬元,在研,主持。

河南逸祥橫向項目,衛生用品非織造材料關鍵技術及應用,2024.2-2026.1,50萬元,在研,主持。

佛山必得福橫向項目,紡熔醫衛防護非織造材料關鍵制備技術及産業化,2021.9-2023.8,20萬元,已結題,主持。

康奈爾大學-諾華諾德校企合作項目,納米纖維免疫隔離人工胰腺的開發,2018.1-2021.6,3498萬元,已結題,參與。

National Institute of Health (1 R01 DK105967-01A1),Engineering an Islet Thread from for type 1 diabetes,2018.7-2023.6.1221萬元,在研,參與。

Juvenile Diabetes Research Foundation,Engineering A Highly Vascularized and Stackable Encapsulation Device,2017.9-2018.8,95萬元,已結題,參與。

國家自然科學基金青年科學基金項目,51403033,表面具有取向溝槽結構的超細纖維制備及其對細胞生長作用的研究,2015-2017,25萬元,已結題,參與。


代表論文

(#代表共同第一作者,*代表通訊作者)

1.W. Liu, J.A. Flanders, L.-H. Wang, Q. Liu, D.T. Bowers, K. Wang, A. Chiu, X. Wang, A.U. Ernst, K. Shariati, J.S. Caserto, B. Parker, D. Gao, M.D. Plesser, L.G. Grunnet, C. Rescan, R. Pimentel Carletto, L. Winkel, J.M. Melero-Martin, M. Ma*, A safe, fibrosis-mitigating, and scalable encapsulation device supports long-term function of insulin-producing cells.Small 18(8) (2022) 2104899(IF: 13.3, Citation 29).

2.W. Liu#, Y.S. Zhang#*, M.A. Heinrich#, F. De Ferrari, H.L. Jang, S.M. Bakht, M.M. Alvarez, J. Yang, Y.-C. Li, G. Trujillo-de Santiago, A.K. Miri, K. Zhu, P. Khoshakhlagh, G. Prakash, H. Cheng, X. Guan, Z. Zhong, J. Ju, G.H. Zhu, X. Jin, S.R. Shin, M.R. Dokmeci, A. Khademhosseini*, Rapid continuous multimaterial extrusion bioprinting. Advanced Materials 29(3) (2017) 1604630(IF: 29.4, Citation 435).

3.K. Shariati, A.S. Ling, S. Fuchs, B. Dillenburger, W. Liu*, M. Ma*, Hylozoic by design: converging material and biological complexities for cell-driven living materials with 4d behaviors,Advanced Functional Materials 32(7) (2022) 2108057 (IF: 19.0, Citation 14)

4.C. Fang, Y. Gu, H. Shi, J. Hu, Y. Wang, M. Pan, J. Feng, Y. Li, Y. Ma, T. Wang, Y. Wan, W. Liu, S.V. Kostjuk, M. Malkoch, W. Liu*, An autoclavable and transparent thermal cutter for reliably sealing wet nanofibrous membranes, Nano Letters (2024)(IF: 10.8)

5.M.A. Heinrich#, W. Liu#, A. Jimenez, J. Yang, A. Akpek, X. Liu, Q. Pi, X. Mu, N. Hu, R.M. Schiffelers, J. Prakash, J. Xie, Y.S. Zhang*, 3D bioprinting: from benches to translational applications. Small 15(23) (2019) (IF: 13.3, Citation 397).

6.Y. Wang, X. Zhang, X. Jin*, W. Liu*, An in situ self-charging triboelectric air filter with high removal efficiency, ultra-low pressure drop, superior filtration stability, and robust service life, Nano Energy 105 (2023) 108021(IF: 17.6, Citation 26).

7.D. Gao, A.U. Ernst, X. Wang, L. Wang, W. Liu*, M. Ma*, Engineering a hierarchical biphasic gel for subcutaneous vascularization, Advanced Healthcare Materials 11(19) (2022) 2200922(IF: 10.0, Citation 5).

8.W. Liu, M.A. Heinrich, Y. Zhou, A. Akpek, N. Hu, X. Liu, X. Guan, Z. Zhong, X. Jin, A. Khademhosseini*, Y.S. Zhang*, Extrusion bioprinting of shear-thinning gelatin methacryloyl bioinks, Advanced Healthcare Materials 6(12) (2017) 1601451 (IF: 10.0, Citation 459).

9.W. Liu, Z. Zhong, N. Hu, Y. Zhou, L. Maggio, A. Miri, A. Fragasso, X. Jin, A. Khademhosseini*, Y.S. Zhang*, Coaxial extrusion bioprinting of 3D microfibrous constructs with cell-favorable gelatin methacryloyl microenvironments, Biofabrication 10(2) (2018) 024102 (IF: 9.0, Citation 285).

10.X. Zhang, Y. Wang, W. Liu*, X. Jin*, Needle-punched electret air filters (NEAFs) with high filtration efficiency, low filtration resistance, and superior dust holding capacity, Separation And Purification Technology 282 (2022) 120146(IF: 8.6, Citation 27).

11.D. Gao, Y. Zhang, D.T. Bowers*, W. Liu*, M. Ma*, Functional hydrogels for diabetic wound management, APL Bioengineering 5(3) (2021) 031503(IF: 6.0, Citation 69).

12.X. Fan, X. Bai, L. Tan, C. Fang, X. Shen, H. Xu, Y. Wang, Y. Ma, Y. Li, X. Song, J. Hu, Y. Lu, X. Wei, J. Zhang, F. Li, Z. Zhu, S. Duan, Y. Zhou, H. Wu, W. Liu*, A transparent additive-free fibrous facial mask for skin moisturizing, Macromolecular Rapid Communications 44(17) (2023) 2300180(IF: 4.6, Citation 3).

13.H. Xu, S. Fang, L. Tan, Y. Li, Y. Wang, Y. Ma, X. Liu, B. Zaarour, W. Liu*, A comprehensive evaluation of the most-sold baby diapers on the market, Textile Research Journal (2024) 1-13(IF: 2.3, Citation 1).

14.X. Yuan, J. Zhang, J. Shi, W. Liu, A.S. Kritchenkov, S. Van Vlierberghe, L. Wang, W. Liu*, J. Gao*, Cotton fabric-reinforced hydrogels with excellent mechanical and broad-spectrum photothermal antibacterial properties, Polymers 16(10) (2024) 1346(IF: 5.0).

15.Q. Zhang, J. Chen, Z. He, W. Liu*, A.S. Kritchenkov, L. Wang, W. Liu*, J. Gao*, Fabrication of anti-fatigue double-wrapped yarns with excellent mechanical properties for generating compression fabrics, Polymers, 2024(IF: 5.0).

16.H. Li, W. Liu*, Z. Chen*, Effect of oligolactic acid stereocomplex microplates as rapid crystallization nucleating agents on the properties of poly(L-lactic acid), Polymer Engineering & Science 64(5) (2024) 1958-1970(IF: 3.2).

17.W. Liu#, L. Zhu#, C. Huang, X. Jin*, Direct electrospinning of ultrafine fibers with interconnected macropores enabled by in situ mixing microfluidics, ACS applied materials & interfaces 8(50) (2016) 34870-34878 (IF: 9.5, Citation 38).

18.W. Liu, C. Huang, X. Jin*, Electrospinning of grooved polystyrene fibers: effect of solvent systems, Nanoscale Research Letters 10(1) (2015) 237 (IF: 5.4, Citation 79).

19.W. Liu, C. Huang, X. Jin*, Tailoring the grooved texture of electrospun polystyrene nanofibers by controlling the solvent system and relative humidity, Nanoscale Research Letters 9(1) (2014) 350 (IF: 5.4, Citation 36).

其他論文

20.A.U. Ernst, L.-H. Wang*, S.C. Worland, B.A. Marfil-Garza, X. Wang, W. Liu, A. Chiu, T. Kin, D. O’Gorman, S. Steinschneider, A.K. Datta, K.K. Papas, A.M. James Shapiro, M. Ma*, A predictive computational platform for optimizing the design of bioartificial pancreas devices, Nature Communications 13(1) (2022) 6031(IF: 16.6, Citation 18).

21.Q. Liu, X. Wang, A. Chiu, W. Liu, S. Fuchs, B. Wang, L.-H. Wang, J. Flanders, Y. Zhang, K. Wang, J.M. Melero-Martin, M. Ma*, A zwitterionic polyurethane nanoporous device with low foreign-body response for islet encapsulation, Advanced Materials 33(39) (2021) 2102852(IF: 29.4, Citation 42).

22.Q. Liu, Y. Zhang, W. Liu, L.-H. Wang, Y.W. Choi, M. Fulton, S. Fuchs, K. Shariati, M. Qiao, V. Bernat, M. Ma*, A broad-spectrum antimicrobial and antiviral membrane inactivates sars-cov-2 in minutes, Advanced Functional Materials 31(47) (2021) 2103477(IF: 19.0, Citation 16).

23.L.-H. Wang, A.U. Ernst, J.A. Flanders, W. Liu, X. Wang, A.K. Datta, B. Epel, M. Kotecha, K.K. Papas, M. Ma*, An inverse-breathing encapsulation system for cell delivery, Science Advances 7(20) (2021) eabd5835(IF: 13.6, Citation 57).

24.X. Wang, G. Maxwell Kristina, K. Wang, T. Bowers Daniel, A. Flanders James, W. Liu, L.-H. Wang, Q. Liu, C. Liu, A. Naji, Y. Wang, B. Wang, J. Chen, U. Ernst Alexander, M. Melero-Martin Juan, R. Millman Jeffrey*, M. Ma*, A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes, Science Translational Medicine 13(596) (2021) eabb4601(IF: 17.1, Citation 91).

25.J. Chen, D. Wang, L.-H. Wang, W. Liu, A. Chiu, K. Shariati, Q. Liu, X. Wang, Z. Zhong, J. Webb, R.E. Schwartz, N. Bouklas, M. Ma*, An adhesive hydrogel with “load-sharing” effect as tissue bandages for drug and cell delivery, Advanced Materials 32(43) (2020) 2001628(IF: 29.4, Citation 145).

26.W. Jia, P.S. Gungor-Ozkerim, Y.S. Zhang*, K. Yue, K. Zhu, W. Liu, Q. Pi, B. Byambaa, M.R. Dokmeci, S.R. Shin*, A. Khademhosseini*, Direct 3D bioprinting of perfusable vascular constructs using a blend bioink, Biomaterials 106 (2016) 58-68(IF: 14.0, Citation 922).

27.C. Huang, Y. Ouyang*, H. Niu, N. He, Q. Ke, X. Jin, D. Li, J. Fang, W. Liu, C. Fan, T. Lin*, Nerve Guidance Conduits from Aligned Nanofibers: Improvement of Nerve Regeneration through Longitudinal Nanogrooves on a Fiber Surface, ACS applied materials & interfaces 7(13) (2015) 7189-7196(IF: 9.5, Citation 149).

28. M. Rocca, A. Fragasso, W. Liu, M.A. Heinrich, Y.S. Zhang*, Embedded multimaterial extrusion bioprinting, SLAS Technology 23(2) (2018) 154–163(IF: 2.7, Citation 108).


專利專著


1.Liu, W.; Ma, M.; Flanders, J. A.; Wang, L.; Bowers, D. T. ; Liu, Q., Nanofiber-enabled encapsulation devices and uses thereof (WO2021202945A1,排名:1/6)).

2.一種可滅菌的透明熱切割封口器及其制備方法(申請号:202410502120.2,排名:1/2)

3.一種纖維間相互粘結的紡織材料及其制備方法(申請号:202411504210.7,排名:1/2)

4.一種徑向異構聚丙烯長絲土工布及其制備方法 (申請号:202311574837.2,排名:6/8)

5.一種納米碳酸鈣壓濾水處理方法 (申請号:202410402360.8,排名:3/4)

6.一種高效低阻的空氣過濾材料 (ZL 2022 2 3201204.0,排名:3/11)

7.一種高效低阻複合過濾材料 (ZL 2022 2 3201332.5,排名:3/11)

8.FZ/T 93047-2023針刺機,排名9/18

9.FZ/T 93048.3-2023針刺機用針第三部分:錐形針,排名8/9




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